Apogee Therapeutics (NASDAQ: APGE) is a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare genetic diseases. The company's lead product candidate is APG-103, an oral small molecule drug in development for the treatment of lysosomal storage disorders (LSDs), which are a group of inherited metabolic disorders caused by deficiencies in enzymes that break down complex carbohydrates and proteins.
On August 19, 2021, Apogee Therapeutics announced that its stock had reached a new 52-week high of $38.34 per share on the NASDAQ Global Select Market. This represents an increase of over 60% from the company's previous 52-week low of $23.71, which was reached on March 19, 2021.
The stock price increase can be attributed to several factors, including positive news about APG-103's development and potential commercialization prospects. In July 2021, the company announced that it had completed a Phase 2a clinical trial of APG-103 in patients with Pompe disease, an LSD characterized by muscle weakness, heart failure, and liver enlargement. The trial met its primary endpoint of safety and tolerability, and showed promising signs of efficacy in reducing key biomarkers of the disease.
Additionally, in August 2021, Apogee Therapeutics announced that it had entered into a strategic partnership with Amicus Therapeutics (NASDAQ: FOLD), a biopharmaceutical company focused on rare genetic diseases. Under the terms of the partnership, Amicus will provide funding and support for the development and commercialization of APG-103 in Pompe disease, while Apogee will retain ownership of the drug candidate and all intellectual property rights related to its development.
Overall, the positive news about APG-103's development and potential commercialization prospects has contributed to the increase in Apogee Therapeutics' stock price, which reached a new 52-week high on August 19, 2021.
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